Spectrin Alpha 1 (Erythrocyte Marker)(SPTA1/1832), 1mg/mL [26628-22-8]

Biotium

Spectrin Alpha 1 (Erythrocyte Marker)(SPTA1/1832), 1mg/mL

9

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

SPTA1/1832

1 mg/ml

SPTA1

spectrin alpha, erythrocytic 1

alpha-I spectrin; EL2; elliptocytosis 2; erythroid alpha-spectrin; HPP; HS3; spectrin alpha chain, erythrocyte; spectrin alpha chain, erythrocytic 1; SPH3; SPTA

Mouse

IgG2b

Spectrin alpha chain, erythrocytic 1

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous alpha andbeta chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin alpha I and spectrinbeta I are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrinbeta II (also designated fodrinbeta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Human, Mouse

-20°C

12352203