SPEN-IN-1

MedChem Express

SPEN-IN-1

10

Research Use Only

98.47

C27H20N4O

416.47

SPEN-IN-1 (compound X1) is an inhibitor of SPEN which is a protein factor with a K d value of 47 nM. SPEN-IN-1 has high selectivity for RepA, a 431-nucleotide domain in Xist (a non-coding RNA prototype) that comprises 8.5 units of a GC-rich motif responsible for gene silencing [1] .

C1(C2=NC3=CC=CC=C3N2)=NNC4=C1C=C(C5=CC=CC(OCC6=CC=CC=C6)=C5)C=C4

2°C to 8°C

12352200