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Spexin [1370290-58-6]

Spexin [1370290-58-6]

TP1930
TargetMol Chemicals
CAS Number1370290-58-6
Product group Chemicals
Molecular Weight1619.9
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Spexin [1370290-58-6]
  • Delivery Days Customer
    16
  • CAS Number
    1370290-58-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Spexin
  • Molecular Formula
    C74H114N20O19S
  • Molecular Weight
    1619.9
  • Scientific Description
    Potent galanin receptor 2/3 (GAL2/GAL3) agonist (EC50 values are 45.7 and 112.2 nM, respectively). Exhibits no significant activity at galanin receptor 1. Endogenous satiety-inducing peptide; inhibits long chain fatty acid uptake by adipocytes and decreases food consumption in diet-induced obese mice and rats. Attenuates LH secretion in goldfish. Exhibits anxiolytic effects in vivo.
  • Shelf life instruction
    3 years
  • SMILES
    C([C@@H](C(N[C@H](C(=O)N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CCC(N)=O)C(N)=O)=O)C)=O)=O)CCCCN)=O)CC(C)C)=O)=O)CC(C)C)=O)CCSC)=O)C)=O)CCC(N)=O)=O)CCC1)[C@@H](C)O)=O)NC([C@H](CC(N)=O)N)=O)C=3C=4C(NC3)=CC=CC4
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Coevolution of the spexin/galanin/kisspeptin family: Spexin activates galanin receptor type II and III. Kim DK et al., 2014 May, Endocrinology
    Read more

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