SPHK1 Polyclonal Antibody
RD80099A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse
TargetSPHK1
Overview
- SupplierReddot Biotech
- Product NameSPHK1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID8877
- Target nameSPHK1
- Target descriptionsphingosine kinase 1
- Target synonymsacetyltransferase SPHK1; SK 1; sphingosine kinase 1; SPHK; SPK 1
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203