Spike (P.1 Variant) (SARS-CoV-2) Ps
78144
ApplicationsNeutralisation/Blocking
Product group Proteins / Signaling Molecules
Overview
- SupplierBPS Bioscience
- Product NameSpike (P.1 Variant) (SARS-CoV-2) Ps
- Delivery Days Customer7
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- FormatThe titer will vary with each lot; the exact value is provided with each shipment.
- Scientific DescriptionIn Brazil, a variant called P.1 was first identified in the summer of 2020. This variant has many mutations that may lead to higher transmissibility and infectivity. The Spike (P.1) (SARS-CoV-2) Pseudotyped Lentiviruses were produced with SARS-CoV-2 Variant Spike (Genbank #QHD43416.1 with P.1 mutations (L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I) as the envelope glycoproteins instead of the commonly used VSVG. These pseudovirions contain the firefly luciferase gene driven by a CMV promoter, therefore, the spike-mediated cell entry can be measured via luciferase activity. The Spike (P.1) (SARS-CoV-2) pseudotyped lentivirus can be used to measure the activity of neutralizing antibody against SARS-CoV-2 (P.1) variant using a Biosafety Level 2 facility.
- Storage Instruction-80°C
- UNSPSC12352202