![Spike Trimer Neutralizing Antibody Spike Trimer Neutralizing Antibody](https://bpsbioscience.com/media/catalog/product/1/0/101061_rbd.png)
Spike Trimer Neutralizing Antibody
![Research Use Only](static/images/certificates/ruo.jpg)
101061
![BPS Bioscience](https://www.bio-connect.nl/wp-content/uploads/2024/03/BPS_logo.png)
ApplicationsFunctional Assay, Neutralisation/Blocking
Product group Antibodies
Overview
- SupplierBPS Bioscience
- Product NameSpike Trimer Neutralizing Antibody
- Delivery Days Customer7
- ApplicationsFunctional Assay, Neutralisation/Blocking
- CertificationResearch Use Only
- ClonalityMonoclonal
- HostHuman
- IsotypeIgG1
- Scientific DescriptionThis antibody is a humanized monoclonal antibody which recognizes SARS-CoV-2 spike RBD and the full-length spike proteins in the native trimeric conformation. This antibody is derived from rabbit monoclonal C-A11 neutralizing antibody (BPS Bioscience, #101024). It cross-reacts with the wildtype as well as the B.1.617.2 (Delta Variant), B.1.617.2.1 (Delta PLUS Variant), B.1.1.7 (Alpha Variant) RBDs and spike protein trimers [See Table of variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Sike protein. This neutralizing antibody has been functionally tested using BPS Bioscience Spike RBD: ACE2 Inhibitor Screening Kits (available for purchase).
- Storage Instruction2°C to 8°C
- UNSPSC12352203