Spike Trimer (S1+S2) (K417T, E484K, N501Y), His-Tag (SARS-CoV-2) Recombinant
100988

ApplicationsNeutralisation/Blocking
Product group Proteins / Signaling Molecules
Overview
- SupplierBPS Bioscience
- Product NameSpike Trimer (S1+S2) (K417T, E484K, N501Y), His-Tag (SARS-CoV-2) Recombinant
- Delivery Days Customer7
- ApplicationsNeutralisation/Blocking
- CertificationResearch Use Only
- Estimated Purity>90%
- Scientific DescriptionRecombinant SARS-CoV-2 Spike protein in its homotrimeric form, containing S1+S2 subunits and encompassing amino acids 16-1213. This protein contains three mutations: K417T, E484K and N501Y that have been found in emerging SARS-CoV-2 Variants of Concern and may lead to higher transmissibility and infectivity. This mutant Spike Trimer will be useful for structure-function studies, testing of neutralizing antibodies, or antibody and drug screening. The construct also contains a C-terminal His-tag. Note that the expected MW of the S1+S2 monomer is 136kDa but migrates at a higher MW in SDS-PAGE due to glycosylation. The recombinant protein is ?90% pure following affinity purification.
- Storage Instruction-80°C
- UNSPSC12352202