Spiradoline

MedChem Express

Spiradoline

9

87151-85-7

Research Use Only

C22H30Cl2N2O2

425.39

Spiradoline (U-62066), an arylacetamide, is a selective kappa opioid receptor (KOR) agonist with a K i of 8.6 nM in guinea pig. The K i values of Spiradoline for micro and delta receptors are 252 nM and 9400 nM, respectively. Spiradoline has potent diuretic, analgesic, antiarrythmic, antitussive, neuroprotective properties and easily penetrates the blood-brain barrier [1] [2] .

ClC1=CC(CC(N([C@H]([C@H](C2)N3CCCC3)CC[C@]42CCCO4)C)=O)=CC=C1Cl

12352200