More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/SPOP Antibody, Biotin conjugated

SPOP Antibody, Biotin conjugated

CSB-PA022601LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetSPOP
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    Cusabio
  • Product Name
    SPOP Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID8405
  • Target name
    SPOP
  • Target description
    speckle type BTB/POZ protein
  • Target synonyms
    BTBD32; HIB homolog 1; NEDMACE; NEDMIDF; NSDVS1; NSDVS2; roadkill homolog 1; speckle-type POZ protein; TEF2
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO43791
  • Protein Name
    Speckle-type POZ protein
  • Scientific Description
    Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of H2AFY and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. The cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex containing homodimeric SPOP has higher ubiquitin ligase activity than the complex that contains the heterodimer formed by SPOP and SPOPL.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203