SpoT Protein, E. coli, Recombinant (His & Myc)

TargetMol Chemicals

SpoT Protein, E. coli, Recombinant (His & Myc)

16

Research Use Only

86.8 kDa (predicted)

In eubacteria ppGpp (guanosine 3-diphosphate 5-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes both the synthesis and degradation of ppGpp. The second messengers ppGpp and c-di-GMP together control biofilm formation in response to translational stress; ppGpp represses biofilm formation while c-di-GMP induces it. ppGpp activates transcription of CsrA-antagonistic small RNAs CsrB and CsrC, which downregulate CsrAs action on translation during the stringent response.

-20°C

12352200