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SR-1277

HY-108907
MedChem Express
CAS Number1446715-47-4
Product group Chemicals
Molecular Weight477.50
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Overview

  • Supplier
    MedChem Express
  • Product Name
    SR-1277 [1446715-47-4]
  • Delivery Days Customer
    10
  • CAS Number
    1446715-47-4
  • Certification
    Research Use Only
  • Molecular Formula
    C21H19N9O3S
  • Molecular Weight
    477.50
  • Scientific Description
    SR-1277 is a potent, selective and ATP competitive CK1delta/epsilon inhibitor, with IC 50 s of 49 nM and 260 nM, respectively. SR-1277 also inhibits FLT3 , CDK4/cyclin D1 , CDK6/cyclin D3 and CDK9/cyclin K , with IC 50 s of 305 nM, 1340 nM, 311 nM and 109 nM, respectively. SR-1277 can be used for the research of cancer [1] .
  • SMILES
    O=[N+](C1=C2C(N=C(CNC3=C4N=CN(C5=CSC=C5)C4=NC(N6CCOCC6)=N3)N2)=CC=C1)[O-]
  • UNSPSC
    12352200