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Chemical Structure
Chemical Structure
Chemical Structure

SR3677 [1072959-67-1]

Research Use Only
SYN-1083
SYNkinase
CAS Number1072959-67-1
Product group Chemicals
Estimated Purity>95%
Molecular Weight408.5
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Packing Size
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Overview

  • Supplier
    SYNkinase
  • Product Name
    SR3677 [1072959-67-1]
  • Delivery Days Customer
    10
  • CAS Number
    1072959-67-1
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Molecular Formula
    C22H24N4O4
  • Molecular Weight
    408.5
  • Scientific Description
    Chemical. CAS: 1072959-67-1. Formula: C22H24N4O4. MW: 408.5. Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively). SR-3677 had an IC(50) of approximately 3nM in enzyme and cell based assays and had an off-target hit rate of 1.4% against 353 kinases, and inhibited only 3 out of 70 non-kinase enzymes and receptors. - Potent and selective Rho-kinase inhibitor (IC50 values are 3 and 56 nM for ROCK-II and ROCK-I respectively). SR-3677 had an IC(50) of approximately 3nM in enzyme and cell based assays and had an off-target hit rate of 1.4% against 353 kinases, and inhibited only 3 out of 70 non-kinase enzymes and receptors.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352200