WB analysis of Jurkat whole cell lysate using GTX81061 SREBP1 antibody, Internal. Loading : 20 microg per lane Dilution : 1:1000
WB analysis of Jurkat whole cell lysate using GTX81061 SREBP1 antibody, Internal. Loading : 20 microg per lane Dilution : 1:1000
SREBP1 antibody, Internal
GTX81061
Overview
- SupplierGeneTex
- Product NameSREBP1 antibody, Internal
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. IHC-P: 1:10-1:50. FACS: 1:10-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- FormulationLiquid
- Gene ID6720
- Target nameSREBF1
- Target descriptionsterol regulatory element binding transcription factor 1
- Target synonymsbHLHd1; class D basic helix-loop-helix protein 1; HMD; IFAP2; SREBP1; sterol regulatory element-binding protein 1
- Protein IDP36956
- Protein NameSterol regulatory element-binding protein 1
- Scientific DescriptionThis gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1), which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis. The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum. Following cleavage, the mature protein translocates to the nucleus and activates transcription. This cleaveage is inhibited by sterols. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative promoter usage and splicing result in multiple transcript variants, including SREBP-1a and SREBP-1c, which correspond to RefSeq transcript variants 2 and 3, respectively. [provided by RefSeq, Nov 2017]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203