Western blot analysis of extracts from HeLa cells, using SRY antibody.
Western blot analysis of extracts from HeLa cells, using SRY antibody.
SRY Antibody
CSB-PA985423
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetSRY
Overview
- SupplierCusabio
- Product NameSRY Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6736
- Target nameSRY
- Target descriptionsex determining region Y
- Target synonymsessential protein for sex determination in human males; sex-determining region on Y; sex-determining region Y protein; SRXX1; SRXY1; TDF; TDY; testis-determining factor on Y; truncated sex-determining region Y protein
- HostRabbit
- IsotypeIgG
- Protein IDQ05066
- Protein NameSex-determining region Y protein
- Scientific DescriptionTranscriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells By similarity. In male adult brain involved in the maintenance of motor functions of dopaminergic neurons By similarity. Involved in different aspects of gene regulation including promoter activation or repression By similarity. Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5-[AT]AACAA[AT]-3. Sinclair A.H., Nature 346:240-244(1990). Su H., Am. J. Hum. Genet. 52:24-38(1993). Behlke M.A., Genomics 17:736-739(1993).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203