ssK36

MedChem Express

ssK36

5

Research Use Only

ssK36 is a supersubstrate peptide of the histone methyltransferase (SET) domain protein 2 ( SETD2 ), and ssK36 is designed for the SETD2 protein, a specific PKMT. It is responsible in human cells for adding methyl groups to the 36th lysine residue of histone H3 ( H3K36 ) to form H3K36me3. ssK36 can be methylated by SETD2 at a rate more than 100 times faster than the natural substrate H3K36. ssK36 can be used to study the catalytic mechanism of PKMTs, especially substrate specificity and catalytic efficiency [1] .

12352202