Western blot analysis of extracts from COLO205 cells, using ST5 antibody.
ST5 Antibody
CSB-PA195797
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetDENND2B
Overview
- SupplierCusabio
- Product NameST5 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID6764
- Target nameDENND2B
- Target descriptionDENN domain containing 2B
- Target synonymsDENN domain-containing protein 2B; DENN/MADD domain containing 2B; heLa tumor suppression 1; HTS1; p126; ST5; suppression of tumorigenicity 5 protein
- HostRabbit
- IsotypeIgG
- Protein IDP78524
- Protein NameSuppression of tumorigenicity 5 protein
- Scientific DescriptionGuanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth. Lichy J.H., Nucleic Acids Res. 24:4700-4708(1996). Amid C., Cytogenet. Cell Genet. 93:284-290(2001). Lichy J.H., Cell Growth Differ. 3:541-548(1992).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203