ST5 Antibody, FITC conjugated

Cusabio

ST5 Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

DENND2B

DENN domain containing 2B

DENN domain-containing protein 2B; DENN/MADD domain containing 2B; heLa tumor suppression 1; HTS1; p126; ST5; suppression of tumorigenicity 5 protein

Rabbit

IgG

Suppression of tumorigenicity 5 protein

Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May be involved in cytoskeletal organization and tumorogenicity. Isoform 1 seems to be involved in a signaling transduction pathway leading to activation of MAPK1/ERK2. Isoform 3 may block ERK2 activation stimulated by ABL1. Isoform 3 may alter cell morphology and cell growth.

Human

-20°C or -80°C

12352203