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STARD4 Polyclonal Antibody

RD253335A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSTARD4
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    STARD4 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.2 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID134429
  • Target name
    STARD4
  • Target description
    StAR related lipid transfer domain containing 4
  • Target synonyms
    StAR-related lipid transfer (START) domain containing 4; stAR-related lipid transfer protein 4; START domain containing 4, sterol regulated; START domain-containing protein 4
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203