STARD4 Polyclonal Antibody
RD266635A
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse, Rat
TargetSTARD4
Overview
- SupplierReddot Biotech
- Product NameSTARD4 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID134429
- Target nameSTARD4
- Target descriptionStAR related lipid transfer domain containing 4
- Target synonymsStAR-related lipid transfer (START) domain containing 4; stAR-related lipid transfer protein 4; START domain containing 4, sterol regulated; START domain-containing protein 4
- HostRabbit
- IsotypeIgG
- Scientific DescriptionCholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203