STAT2 Antibody
![Research Use Only](static/images/certificates/ruo.jpg)
ORB639944
Overview
- SupplierBiorbyt
- Product NameSTAT2 Antibody
- Delivery Days Customer16
- ApplicationsImmunoHistoChemistry
- Applications SupplierImmunohistochemistry (FFPE): 1-2ug/ml IHC-P
- CertificationResearch Use Only
- Clone IDSTAT2/2650
- IsotypeIgG
- Scientific DescriptionMembrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.
- UNSPSC12352203