STAT2(STAT2/2650), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

STAT2(STAT2/2650), CF405S conjugate, 0.1mg/mL

9

ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

STAT2/2650

0.1 mg/ml

Other Conjugate

STAT2

signal transducer and activator of transcription 2

IMD44; interferon alpha induced transcriptional activator; ISGF-3; P113; PTORCH3; signal transducer and activator of transcription 2; signal transducer and activator of transcription 2, 113kDa; STAT113

Mouse

IgG1

Signal transducer and activator of transcription 2

Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C

12352203