STAT3-IN-13

MedChem Express

STAT3-IN-13

10

Research Use Only

99.01

C21H20N6O3S

436.49

STAT3-IN-13 (compound 6f) is a potent STAT3 inhibitor. STAT3-IN-13 has anti-proliferative effects and binds to the STAT3 SH2 domain with a KD of 0.46 microM. STAT3-IN-13 inhibits the phosphorylation of STAT3 Y705 and downstream target gene expression. STAT3-IN-13 induces apoptosis in vitro and suppresses the growth and metastasis of tumor in vivo. STAT3-IN-13 can be used for cancer research[1].

N#CC1=C(SC2=C1CCN(C2)C(NC3=CC=C(C=C3)OC)=O)NC(C(C=N4)=CN4C)=O

-20°C,2°C to 8°C

12352200