STAT3-IN-15

TargetMol Chemicals

STAT3-IN-15

72

Chemical

Research Use Only

STAT3-IN-15

C20H17F3N2O3S

422.42

STAT3-IN-15, a potent and orally active inhibitor targeting STAT3, effectively combats idiopathic pulmonary fibrosis (IPF) by hindering STAT3 phosphorylation. Additionally, it impedes TGF-beta1-induced migration and deformation of epithelial cells and prevents epithelial-mesenchymal transition (EMT), offering a multifaceted approach against IPF.

3 years

C1CN(CCN1CC2=CC(=C(C=C2F)F)F)C(=O)C3=CC4=CC=CC=C4S3(=O)=O

-20°C

51202000