STAT3-IN-18 [2668267-41-0]

TargetMol Chemicals

STAT3-IN-18 [2668267-41-0]

16

Chemical

Research Use Only

STAT3-IN-18

C18H24Cl2N2O6Pt

630.38

STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and exhibits anti-proliferative properties. It promotes apoptosis by activating caspase-3 and elevating levels of cleaved polyADP-ribose polymerase, in addition to enhancing maturation and antigen presentation in dendritic cells. Moreover, STAT3-IN-18 has demonstrated in vivo safety.

3 years

-20°C

51202000