STAT3-IN-18 [2668267-41-0]
T79609
Overview
- SupplierTargetMol Chemicals
- Product NameSTAT3-IN-18 [2668267-41-0]
- Delivery Days Customer16
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameSTAT3-IN-18
- Molecular FormulaC18H24Cl2N2O6Pt
- Molecular Weight630.38
- Scientific DescriptionSTAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and exhibits anti-proliferative properties. It promotes apoptosis by activating caspase-3 and elevating levels of cleaved polyADP-ribose polymerase, in addition to enhancing maturation and antigen presentation in dendritic cells. Moreover, STAT3-IN-18 has demonstrated in vivo safety.
- Shelf life instruction3 years
- SMILESC(=C/C1=CC=C(OCC([O-][Pt+4]([Cl-])([Cl-])([NH3])([NH3])[OH-])=O)C=C1)\C2=CC(OC)=CC(OC)=C2
- Storage Instruction-20°C
- UNSPSC51202000