Bio-Connect

STAT3-IN-18 [2668267-41-0]

Research Use Only
T79609
TargetMol Chemicals
Molecular Weight630.38
Product group Chemicals
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    STAT3-IN-18 [2668267-41-0]
  • Delivery Days Customer
    16
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    STAT3-IN-18
  • Molecular Formula
    C18H24Cl2N2O6Pt
  • Molecular Weight
    630.38
  • Scientific Description
    STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and exhibits anti-proliferative properties. It promotes apoptosis by activating caspase-3 and elevating levels of cleaved polyADP-ribose polymerase, in addition to enhancing maturation and antigen presentation in dendritic cells. Moreover, STAT3-IN-18 has demonstrated in vivo safety.
  • Shelf life instruction
    3 years
  • SMILES
    C(=C/C1=CC=C(OCC([O-][Pt+4]([Cl-])([Cl-])([NH3])([NH3])[OH-])=O)C=C1)\C2=CC(OC)=CC(OC)=C2
  • Storage Instruction
    -20°C
  • UNSPSC
    51202000