Bio-Connect

STAT3-IN-18

Research Use Only
HY-155808
MedChem Express
Molecular Weight630.38
Product group Chemicals
Price on request
Packing Size
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    STAT3-IN-18
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Molecular Formula
    C18H24Cl2N2O6Pt
  • Molecular Weight
    630.38
  • Scientific Description
    STAT3-IN-18 (compound SPP) is a platinum (IV) complex with an axial ligand derived from sandalwood. STAT3-IN-18 inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, with anti-proliferative activity. STAT3-IN-18 activates caspase-3 and increases cleaved polyADP-ribose polymerase to induce apoptosis. STAT3-IN-18 promotes maturation and antigen presentation of dendritic cells and demonstrates safety in vivo.
  • SMILES
    [Cl-][Pt+4]([Cl-])([NH3])([NH3])([OH-])[O-]C(COC(C=C1)=CC=C1/C=C/C2=CC(OC)=CC(OC)=C2)=O
  • UNSPSC
    12352200