STAT3-IN-31

MedChem Express

STAT3-IN-31

9

Research Use Only

C16H15NO3S

301.36

STAT3-IN-31 (compound K2071) is a STATtic-derived STAT3 and mitotic inhibitor. STAT3-IN-31 blocks mitotic progression and affects the formation of mitotic spindles. STAT3-IN-31 also affects glioblastoma cell migration and inhibits cell proliferation in tumor spheroids. STAT3-IN-31 is also able to induce glioblastoma senescence, inhibit the growth of Temozolomide (HY-17364)-resistant cells and the secretion of the pro-inflammatory cytokine monocyte chemoattractant protein MCP-1[1].

COC1=CC=C(C=C1)CNC2=CC=C(C=CS3(=O)=O)C3=C2

12352200