STAT4 Polyclonal Antibody
RD84202A
ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSTAT4
Overview
- SupplierReddot Biotech
- Product NameSTAT4 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, Western Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID6775
- Target nameSTAT4
- Target descriptionsignal transducer and activator of transcription 4
- Target synonymssignal transducer and activator of transcription 4; signal transducer and activator of transcription 4 variant 3; SLEB11
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203