
Anti-STAT5 pY694 (MOUSE) Monoclonal Antibody detecting STAT5 in 3T3 cells (immunofluorescent STED microscopy). Red represents STAT5 pY694 protein. Green represents tubulin.
STAT5A (phospho Tyr694) antibody [5F6.F1]
GTX48647
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetStat5a
Overview
- SupplierGeneTex
- Product NameSTAT5A (phospho Tyr694) antibody [5F6.F1]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:2000. ICC/IF: 1:50-1:1000. IHC-P: 20-40 microg/mL. ELISA: 1:20000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID5F6.F1
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID20850
- Target nameStat5a
- Target descriptionsignal transducer and activator of transcription 5A
- Target synonymsAA959963; mammary gland factor STAT5A; signal transducer and activator of transcription 5A; STA; STAT5
- HostMouse
- IsotypeIgG1
- Protein IDP42230
- Protein NameSignal transducer and activator of transcription 5A
- Scientific DescriptionSignal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5and Stat5. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus.
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203