The image is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA699319(STAT5B Antibody) at dilution 1/10. (Original magnification: x200)
The image is immunohistochemistry of paraffin-embedded Human lymphoma tissue using CSB-PA699319(STAT5B Antibody) at dilution 1/10. (Original magnification: x200)
STAT5B Antibody
CSB-PA699319
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetSTAT5B
Overview
- SupplierCusabio
- Product NameSTAT5B Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID6777
- Target nameSTAT5B
- Target descriptionsignal transducer and activator of transcription 5B
- Target synonymsGHISID2; signal transducer and activator of transcription 5B; STAT5; transcription factor STAT5B
- HostRabbit
- IsotypeIgG
- Protein IDP51692
- Protein NameSignal transducer and activator of transcription 5B
- Scientific DescriptionThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203