STEAP3 antibody

GeneTex

STEAP3 antibody

9

WB: 1 - 2 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

STEAP3

STEAP3 metalloreductase

AHMIO2; dudlin-2; dudulin-2; metalloreductase STEAP3; pHyde; six-transmembrane epithelial antigen of prostate 3; STEAP family member 3, metalloreductase; STMP3; TSAP6; tumor suppressor pHyde; tumor suppressor-activated pathway protein 6

Rabbit

IgG

Metalloreductase STEAP3

The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells. This STEAP3 antibody does not cross-react with other STEAP proteins.

-20°C or -80°C,2°C to 8°C

12352203