Stevioside hydrate [57817-89-7]

AdipoGen Life Sciences

Stevioside hydrate

10

57817-89-7

Research Use Only

>95%

C38H60O18 . xH2O

804.9 (anhydrous basis)

Chemical. CAS: 57817-89-7 (anhydrous). Formula: C38H60O18 . xH2O. MW: 804.9 (anhydrous basis). Isolated from Stevia rebaudiana. Noncaloric natural sweetener, 300 times more potent than sucrose. Antidiabetic. Antihyperglycaemic and antihypoglycaemic. Potentiates insulin secretion. Enhances acetyl-CoA carboxylase (ACC) gene expression. Increases insulin sensitivity. Antihypertensive. Ca2+ influx inhibitor. Anticancer compound. Chemopreventive. Anti-inflammatory. IKKbeta, NF-kappaB and MAPK signaling inhibitor. Induces TNF-alpha, IL-1beta and nitric oxide release. Immunomodulator. Increasees phagocytic activity, haemagglutination antibody titre, delayed type hypersensitivity. Increased proliferation in LPS and Con A stimulated B and T cells. Peripheral micro-opioid receptors activator. Important for regulation of glucose homeostasis. Anti-atherosclerotic. Review. - Noncaloric natural sweetener, 300 times more potent than sucrose [1]. Antidiabetic. Antihyperglycaemic and antihypoglycaemic. Potentiates insulin secretion. Enhances acetyl-CoA carboxylase (ACC) gene expression. Increases insulin sensitivity. [2, 4, 6-9, 11]. Antihypertensive. Ca2+ influx inhibitor [3, 6]. Anticancer compound [5]. Chemopreventive [14]. Anti-inflammatory. IKKbeta, NF-kappaB and MAPK signaling inhibitor. Induces TNF-alpha, IL-1beta and nitric oxide release [10, 17, 18]. Immunomodulator. Increasees phagocytic activity, haemagglutination antibody titre, delayed type hypersensitivity. Increased proliferation in LPS and Con A stimulated B and T cells [12]. Peripheral micro-opioid receptors activator. Important for regulation of glucose homeostasis [15]. Anti-atherosclerotic [16]. Review [13].

[H][C@@]12CC[C@@]3(C[C@]1(CC3=C)CC[C@]1([H])[C@@](C)(CCC[C@@]21C)C(=O)O[C@@H]1OC(CO)[C@@H](O)[C@@H](O)C1O)O[C@@H]1OC(CO)[C@@H](O)[C@@H](O)C1O[C@@H]1OC(CO)[C@@H](O)[C@@H](O)C1O

2°C to 8°C

12352200