sTGFBR3 antagonist 1

TargetMol Chemicals

sTGFBR3 antagonist 1

9

Research Use Only

sTGFBR3 antagonist 1 (Compound p24) is an antagonist of soluble transforming growth factor beta receptor 3 (sTGFBR3) that activates the TGF-beta signaling pathway while inhibiting the IkappaBalpha/NF-kappaB signaling pathway. It inhibits the release of NO induced by LPS in BV2 cells with an IC50 of 0.52 microM. sTGFBR3 antagonist 1 exhibits anti-inflammatory and neuroprotective activities and can enhance the permeability of the blood-brain barrier (BBB). This compound is applicable in research related to Alzheimers disease.

-20°C

12352200