IHC-P analysis of human spleen tissue using GTX85441 STIM2 antibody. Working concentration : 2.5 microg/ml
IHC-P analysis of human spleen tissue using GTX85441 STIM2 antibody. Working concentration : 2.5 microg/ml
STIM2 antibody
GTX85441
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetSTIM2
Overview
- SupplierGeneTex
- Product NameSTIM2 antibody
- Delivery Days Customer9
- Antibody SpecificityThis antibody is specific for STIM2 C-Terminus
- Application Supplier NoteWB: 0.5 - 1 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID57620
- Target nameSTIM2
- Target descriptionstromal interaction molecule 2
- Target synonymsstromal interaction molecule 2
- HostRabbit
- IsotypeIgG
- Protein IDQ9P246
- Protein NameStromal interaction molecule 2
- Scientific DescriptionIn T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203