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STL127705

HY-122727
MedChem Express
CAS Number1326852-06-5
DownloadMSDS
Product group Chemicals
Estimated Purity98.0
Molecular Weight437.42
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Overview

  • Supplier
    MedChem Express
  • Product Name
    STL127705 [1326852-06-5]
  • Delivery Days Customer
    10
  • CAS Number
    1326852-06-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Molecular Formula
    C22H20FN5O4
  • Molecular Weight
    437.42
  • Scientific Description
    STL127705 (Compound L) is a potent Ku 70/80 heterodimer protein inhibitor with an IC 50 of 3.5 microM. STL127705 interferes the binding of Ku70/80 to DNA and by inhibits the activation of the DNA-PKCS kinase. STL127705 shows antiproliferative and anticancer activity. STL127705 induces apoptosis [1] [2] .
  • SMILES
    O=C1NC2=NC(NCCC3=CC=C(OC)C(OC)=C3)=NC=C2C(N1C4=CC=CC(F)=C4)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200