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ProductsBack/Streptochlorin [120191-51-7]
Chemical Structure
Chemical Structure
Chemical Structure

Streptochlorin [120191-51-7]

Research Use Only
AG-CN2-0141
AdipoGen Life Sciences
CAS Number120191-51-7
DownloadMSDS
Product group Chemicals
Estimated Purity>95%
Molecular Weight218.6
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    Streptochlorin [120191-51-7]
  • Delivery Days Customer
    10
  • CAS Number
    120191-51-7
  • Certification
    Research Use Only
  • Estimated Purity
    >95%
  • Hazard Information
    Warning
  • Molecular Formula
    C11H7ClN2O
  • Molecular Weight
    218.6
  • Scientific Description
    Antibiotic [1]. TNF-alpha-induced NF-kappaB activation inhibitor [1]. Antiangiogenic [1]. Apoptosis inducer [2-4]. Anticancer compound. Selective cytotoxic against several cancer cell lines [2-4]. Tyrosinase inhibitor [5]. - Chemical. CAS: 120191-51-7. Formula: C11H7ClN2O. MW: 218.6. Isolated from Streptomyces roseolilacinus. Antibiotic. TNF-alpha-induced NF-kappaB activation inhibitor. Antiangiogenic. Apoptosis inducer. Anticancer compound. Selective cytotoxic against several cancer cell lines. Tyrosinase inhibitor.
  • SMILES
    ClC1=C(OC=N1)C1=CNC2=CC=CC=C12
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

References

  • Streptochlorin, a marine natural product, inhibits NF-kappaB activation and suppresses angiogenesis in vitro: I. K. Choi, et al.; J. Microbiol. Biotechnol. 17, 1338 (2007)
  • Isolation and structure determination of streptochlorin, an antiproliferative agent from a marine-derived Streptomyces sp. 04DH110: H. J. Shin, et al.; J. Microbiol. Biotechnol. 17, 1403 (2007)
  • Streptochlorin isolated from Streptomyces sp. induces apoptosis in human hepatocarcinoma cells through a reactive oxygen species-mediated mitochondrial pathway: D. Y. Shin, et al.; J. Microbiol. Biotechnol. 18, 1862 (2008)
  • Induction of apoptosis by streptochlorin isolated from Streptomyces sp. in human leukemic U937 cells: C. Park, et al.; Toxicol. In Vitro 22, 1573 (2008)
  • Physicochemical characters of a tyrosinase inhibitor produced by Streptomyces roseolilacinus NBRC 12815: T. Nakashima, et al.; Biol. Pharm. Bull. 32, 832 (2009)