STT3A Antibody, Biotin conjugated

Cusabio

STT3A Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

STT3A

STT3 oligosaccharyltransferase complex catalytic subunit A

B5; dolichyl-diphosphooligosaccharide protein glycotransferase; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A; integral membrane protein 1; integral transmembrane protein 1; ITM1; oligosaccharyl transferase subunit STT3A; STT3, subunit of the oligosaccharyltransferase complex, homolog A; STT3-A; STT3A, catalytic subunit of the oligosaccharyltransferase complex; STT3A, subunit of the oligosaccharyltransferase complex (catalytic); TMC; transmembrane conserved; transmembrane protein TMC

Rabbit

IgG

Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A

Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in complex substrate specificity. STT3A is present in the majority of OST complexes and mediates cotranslational N-glycosylation of most sites on target proteins, while STT3B-containing complexes are required for efficient cotranslational glycosylation and mediate glycosylation of sites that have been skipped by STT3A.

Human

-20°C or -80°C

12352203