Sulconazole mononitrate [61318-91-0]

TargetMol Chemicals

Sulconazole mononitrate

9

61318-91-0

Chemical

Research Use Only

Sulconazole mononitrate

99.17%

C18H15Cl3N2S HNO3

460.76

Sulconazole mononitrate (Exelderm) is the nitrate salt form of sulconazole, a synthetic imidazole derivative with the antifungal property. Sulconazole mononitrate inhibits fungal cytochrome P-450 sterol C-14 alpha-demethylation, resulting in the accumulation of fungal 14 alpha-methyl sterols and inhibition of the synthesis of ergosterol, an important component of the fungal cell membrane. Inhibition of ergosterol synthesis leads to a disruption of cell membrane permeability, and ultimately inhibition of cell wall synthesis. In addition, Sulconazole mononitrate seems to interfere with the autolytic degradation of fungal DNA and RNA.

3 years

c1cc(ccc1CSC(Cn1ccnc1)c1c(cc(cc1)Cl)Cl)Cl.[N+](=O)(O)[O-]

-20°C

12352200