SUR2A antibody

Biorbyt

SUR2A antibody

16

1 microg/ml of SMC-431 was sufficient for detection of SUR2A in 20 microg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

WB (1:1000) ICC, IF, IHC, WB

Research Use Only

Monoclonal

N319A/14 (Formerly sold as S319A-14)

1 mg/ml

RPE

Abcc9

ATP-binding cassette, sub-family C (CFTR/MRP), member 9

AI414027; AI449286; ATP-binding cassette sub-family C member 9; ATP-binding cassette transporter sub-family C member 9; SU; sulfonylurea receptor 2; sulfonylurea-binding protein 2; SUR; Sur2; SUR2A; SUR2B

Mouse

IgG2a

ATP-binding cassette sub-family C member 9

Mouse monoclonal to SUR2A (RPE). Sulfonylurea receptors (SUR) are membrane proteins which are the molecular targets of the sulfonylurea class of anti-diabetic drugs whose mechanism of action is to promote insulin release from pancreatic beta cells. More specifically, SUR proteins are subunits of the inward-rectifier potassium ion channels Kir6. x (6. 1 and 6. 2). The association of four K ir6. x and four SUR subunits form an ion conducting channel commonly referred to as the K ATP channel. The primary function of the sulfonylurea receptor is to sense intracellular levels of the nucleotides ATP and ADP and in response facilitate the open or closing its associated Kir 6. x potassium channel. Hence the K ATP channel monitors the energy balance within the cell..

Human, Mouse, Rat

See Manual

12352203