SUV39H1 antibody [N3C3]
GTX112263
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Monkey, Mouse
TargetSUV39H1
Overview
- SupplierGeneTex
- Product NameSUV39H1 antibody [N3C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.52 mg/ml
- ConjugateUnconjugated
- Gene ID6839
- Target nameSUV39H1
- Target descriptionSUV39H1 histone lysine methyltransferase
- Target synonymsH3-K9-HMTase 1; histone H3-K9 methyltransferase 1; histone-lysine N-methyltransferase SUV39H1; histone-lysine N-methyltransferase, H3 lysine-9 specific 1; KMT1A; lysine N-methyltransferase 1A; MG44; position-effect variegation 3-9 homolog; Su(var)3-9 homolog 1; suppressor of variegation 3-9 homolog 1; SUV39H
- HostRabbit
- IsotypeIgG
- Protein IDO43463
- Protein NameHistone-lysine N-methyltransferase SUV39H1
- Scientific DescriptionThis gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq]
- ReactivityHuman, Monkey, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice. Lee JE et al., 2020 Jun 5, Commun BiolRead more
- Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction. Ishiguro K et al., 2017 Jul, Clin ImmunolRead more
- G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response. Luo CW et al., 2017 Sep, Radiother OncolRead more
- In vitro hydroquinone-induced instauration of histone bivalent mark on human retroelements (LINE-1) in HL60 cells. Mancini M et al., 2017 Apr, Toxicol In VitroRead more
- Role of the histone H3 lysine 9 methyltransferase Suv39 h1 in maintaining Epsteinn-Barr virus latency in B95-8 cells. Imai K et al., 2014 May, FEBS JRead more
- The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression. Babbio F et al., 2012 Nov 15, OncogeneRead more