Bio-Connect

SUV39H1 antibody [N3C3]

GTX112263
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Monkey, Mouse
TargetSUV39H1
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Overview

  • Supplier
    GeneTex
  • Product Name
    SUV39H1 antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.52 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6839
  • Target name
    SUV39H1
  • Target description
    SUV39H1 histone lysine methyltransferase
  • Target synonyms
    H3-K9-HMTase 1; histone H3-K9 methyltransferase 1; histone-lysine N-methyltransferase SUV39H1; histone-lysine N-methyltransferase, H3 lysine-9 specific 1; KMT1A; lysine N-methyltransferase 1A; MG44; position-effect variegation 3-9 homolog; Su(var)3-9 homolog 1; suppressor of variegation 3-9 homolog 1; SUV39H
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO43463
  • Protein Name
    Histone-lysine N-methyltransferase SUV39H1
  • Scientific Description
    This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq]
  • Reactivity
    Human, Monkey, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice. Lee JE et al., 2020 Jun 5, Commun Biol
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  • Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction. Ishiguro K et al., 2017 Jul, Clin Immunol
    Read more
  • G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response. Luo CW et al., 2017 Sep, Radiother Oncol
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  • In vitro hydroquinone-induced instauration of histone bivalent mark on human retroelements (LINE-1) in HL60 cells. Mancini M et al., 2017 Apr, Toxicol In Vitro
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  • Role of the histone H3 lysine 9 methyltransferase Suv39 h1 in maintaining Epsteinn-Barr virus latency in B95-8 cells. Imai K et al., 2014 May, FEBS J
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  • The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression. Babbio F et al., 2012 Nov 15, Oncogene
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