SUV39H1 antibody [N3C3]
GTX112263
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Monkey, Mouse
TargetSUV39H1
Overview
- SupplierGeneTex
- Product NameSUV39H1 antibody [N3C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.52 mg/ml
- ConjugateUnconjugated
- Gene ID6839
- Target nameSUV39H1
- Target descriptionSUV39H1 histone lysine methyltransferase
- Target synonymsH3-K9-HMTase 1, KMT1A, MG44, SUV39H, histone-lysine N-methyltransferase SUV39H1, Su(var)3-9 homolog 1, histone H3-K9 methyltransferase 1, histone-lysine N-methyltransferase, H3 lysine-9 specific 1, lysine N-methyltransferase 1A, position-effect variegation 3-9 homolog, suppressor of variegation 3-9 homolog 1
- HostRabbit
- IsotypeIgG
- Protein IDO43463
- Protein NameHistone-lysine N-methyltransferase SUV39H1
- Scientific DescriptionThis gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq]
- ReactivityHuman, Monkey, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
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- Luo CW, Wang JY, Hung WC, et al. G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response. Radiother Oncol. 2017,124(3):395-402. doi: 10.1016/j.radonc.2017.03.002Read this paper
- Mancini M, Mandruzzato M, Garzia AC, et al. In vitro hydroquinone-induced instauration of histone bivalent mark on human retroelements (LINE-1) in HL60 cells. Toxicol In Vitro. 2017,40:1-10. doi: 10.1016/j.tiv.2016.12.007Read this paper
- Imai K, Kamio N, Cueno ME, et al. Role of the histone H3 lysine 9 methyltransferase Suv39 h1 in maintaining Epsteinn-Barr virus latency in B95-8 cells. FEBS J. 2014,281(9):2148-58. doi: 10.1111/febs.12768Read this paper
- Babbio F, Pistore C, Curti L, et al. The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression. Oncogene. 2012,31(46):4878-87. doi: 10.1038/onc.2011.641Read this paper



