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SUV39H1 antibody [N3C3]

GTX112263
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Monkey, Mouse
TargetSUV39H1
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Overview

  • Supplier
    GeneTex
  • Product Name
    SUV39H1 antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.52 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID6839
  • Target name
    SUV39H1
  • Target description
    SUV39H1 histone lysine methyltransferase
  • Target synonyms
    H3-K9-HMTase 1, KMT1A, MG44, SUV39H, histone-lysine N-methyltransferase SUV39H1, Su(var)3-9 homolog 1, histone H3-K9 methyltransferase 1, histone-lysine N-methyltransferase, H3 lysine-9 specific 1, lysine N-methyltransferase 1A, position-effect variegation 3-9 homolog, suppressor of variegation 3-9 homolog 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO43463
  • Protein Name
    Histone-lysine N-methyltransferase SUV39H1
  • Scientific Description
    This gene is a member of the suppressor of variegation 3-9 homolog family and encodes a protein with a chromodomain and a C-terminal SET domain. This nuclear protein moves to the centromeres during mitosis and functions as a histone methyltransferase, methylating Lys-9 of histone H3. Overall, it plays a vital role in heterochromatin organization, chromosome segregation, and mitotic progression. [provided by RefSeq]
  • Reactivity
    Human, Monkey, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Lee JE, Kwon HJ, Choi J, et al. Aging increases vulnerability to stress-induced depression via upregulation of NADPH oxidase in mice. Commun Biol. 2020,3(1):292. doi: 10.1038/s42003-020-1010-5
    Read this paper
  • Ishiguro K, Watanabe O, Nakamura M, et al. Inhibition of KDM4A activity as a strategy to suppress interleukin-6 production and attenuate colitis induction. Clin Immunol. 2017,180:120-127. doi: 10.1016/j.clim.2017.05.014
    Read this paper
  • Luo CW, Wang JY, Hung WC, et al. G9a governs colon cancer stem cell phenotype and chemoradioresistance through PP2A-RPA axis-mediated DNA damage response. Radiother Oncol. 2017,124(3):395-402. doi: 10.1016/j.radonc.2017.03.002
    Read this paper
  • Mancini M, Mandruzzato M, Garzia AC, et al. In vitro hydroquinone-induced instauration of histone bivalent mark on human retroelements (LINE-1) in HL60 cells. Toxicol In Vitro. 2017,40:1-10. doi: 10.1016/j.tiv.2016.12.007
    Read this paper
  • Imai K, Kamio N, Cueno ME, et al. Role of the histone H3 lysine 9 methyltransferase Suv39 h1 in maintaining Epsteinn-Barr virus latency in B95-8 cells. FEBS J. 2014,281(9):2148-58. doi: 10.1111/febs.12768
    Read this paper
  • Babbio F, Pistore C, Curti L, et al. The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression. Oncogene. 2012,31(46):4878-87. doi: 10.1038/onc.2011.641
    Read this paper