SV40 T-antigen antibody [PAb416]

GeneTex

SV40 T-antigen antibody [PAb416]

9

GTX16879 recognizes the 94 kDa SV40 large T antigen and the 20.5 kDa SV40 small T antigen.

For IF: Use at a concentration of 1 - 5 microg/ml. For IP: Use at a concentration of 1 - 5 microg/ml. For WB: Use at a concentration of 1 - 5 microg/ml. Predicted molecular weight: 82 kDa and 20 kDa. Optimal dilutions/concentrations should be determined by the researcher.

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

PAb416

0.2 mg/ml

Unconjugated

Mouse

IgG2a

SV40 T antigen is encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the P105 product of the retinoblastoma susceptibility gene.

Virus

2°C to 8°C

12352203