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Swinholide A

BS-75036C
Bioss Antibodies
Estimated Purity>98%
Product group Chemicals
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Overview

  • Supplier
    Bioss Antibodies
  • Product Name
    Swinholide A [95927-67-6]
  • Delivery Days Customer
    16
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Scientific Description
    Cell permeable dimeric dilactone macrolide [1]. Cytotoxic compound [1, 2, 7]. Specific actin filament (F-actin) inhibitor. Disrupts the actin cytoskeleton by sequestering actin dimers and rapidly severing actin filaments (F-actin) [3, 5, 7, 8]. Depolymerizes actin filaments (F-actin) [6]. Antifungal [4]. Apoptosis inducer [9]. Alterates the actin cytoskeleton of GH4 cells and inhibits insulin-increased prolactin gene transcription [10].
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200