
IHC-P analysis of human brain tissue using GTX85140 Synaptopodin antibody. Working concentration : 2.5 microg/ml
Synaptopodin antibody
GTX85140
Overview
- SupplierGeneTex
- Product NameSynaptopodin antibody
- Delivery Days Customer9
- Antibody SpecificityAt least three isoforms of SYNPO are known to exist; this antibody will detect all three isoforms. SYNPO antibody is predicted to not cross-react with other SYNPO family member proteins.
- Application Supplier NoteWB: 1 - 2 microg/mL. IHC-P: 2.5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- Concentration1 mg/ml
- FormulationLiquid
- Gene ID11346
- Target nameSYNPO
- Target descriptionsynaptopodin
- Target synonymssynaptopodin
- Protein IDQ8N3V7
- Protein NameSynaptopodin
- Scientific DescriptionSYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO- mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- STAT3 regulates steady-state expression of synaptopodin in cultured mouse podocytes. Abkhezr M et al., 2015 Feb, Mol PharmacolRead more