Synaptotagmin-1 Protein, Human, Recombinant (His)

TargetMol Chemicals

Synaptotagmin-1 Protein, Human, Recombinant (His)

16

Research Use Only

40.3 kDa (predicted)

Calcium sensor that participates in triggering neurotransmitter release at the synapse. May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes.

-20°C

12352200