Synucleozid

MedChem Express

Synucleozid

10

502139-01-7

Research Use Only

C22H20N6

368.43

Synucleozid (NSC 377363) is a potent inhibitor of the SNCA ?mRNA that encodes alpha-synuclein protein. Synucleozid selectively?targets the alpha-synuclein mRNA 5 UTR at the designed IRE site, decreases the amount of? SNCA mRNA loaded into polysomes and thereby inhibits?SNCA?translation. Synucleozid has the potential for the investigation of Parkinsons disease [1] .

N=C(C1=CC2=C(C=C1)C=C(C3=CC=C(NC4=CC=C(C(N)=N)C=C4)C=C3)N2)N

12352200