SZUH280

MedChem Express

SZUH280

10

Research Use Only

99.38

C36H34N8O8

706.70

SZUH280 is a potent and selective PROTAC HDAC8 degrader with a DC 50 of 0.58 microM in A549 cells. SZUH280 induces cancer cell apoptosis . SZUH280 hampers DNA damage repair in cancer cells, promoting cellular radiosensitization [1] .

O=C(C1=CC=C2C(N(C=C2)CC3=CC=C(C=C3)OCCOCCN4C=C(N=N4)CNC5=CC=CC(C(N6C7C(NC(CC7)=O)=O)=O)=C5C6=O)=C1)NO

-20°C

12352200