T-448

MedChem Express

T-448 [1597426-53-3]

10

1597426-53-3

Research Use Only

98.86

C17H20N4OS.1/2C4H4O4

386.50

T-448 is a specific, orally active and irreversible inhibitor of lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) , with an IC 50 of 22 nM. T-448 enhances H3K4 methylation in primary cultured rat neurons [1] .

O=C(NC1=NN=C(C)S1)C2=CC=CC([C@H]3[C@H](NC4CCC4)C3)=C2.O=C(O)/C=C/C(O)=O.[1/2]

-20°C

12352200