T3Inh-1

MedChem Express

T3Inh-1 [50440-30-7]

10

50440-30-7

Research Use Only

98.82

C27H20N6O3

476.49

T3Inh-1 is a potent and selective inhibitor of ppGalNAc-T3 ( IC 50 =7 microM). T3Inh-1 reduces FGF23 hormone levels in both tissue cells and mice, without causing any toxic side effects. T3Inh-1 also prevents breast cancer cells. The enzyme ppGalNAc-T3 is implicated in at least two medically important pathways: cancer metastasis and stabilization of FGF23 (regulates phosphate levels in the bloodstream) [1] .

O=C(NC1=CC=C(NC2=CC=NC=C2)C=C1)C3=CC=C(NC4=CC=NC5=CC=C([N+]([O-])=O)C=C45)C=C3

-20°C,2°C to 8°C

12352200