The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA269153(TAB1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA269153(TAB1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200)
TAB1 Antibody
CSB-PA269153
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTAB1
Overview
- SupplierCusabio
- Product NameTAB1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID10454
- Target nameTAB1
- Target descriptionTGF-beta activated kinase 1 (MAP3K7) binding protein 1
- Target synonyms3'-Tab1; MAP3K7IP1; mitogen-activated protein kinase kinase kinase 7-interacting protein 1; TAK1-binding protein 1; TGF-beta-activated kinase 1 and MAP3K7-binding protein 1; transforming growth factor beta-activated kinase-binding protein 1
- HostRabbit
- IsotypeIgG
- Protein IDQ15750
- Protein NameTGF-beta-activated kinase 1 and MAP3K7-binding protein 1
- Scientific DescriptionThe protein encoded by this gene was identified as a regulator of the MAP kinase kinase kinase MAP3K7/TAK1, which is known to mediate various intracellular signaling pathways, such as those induced by TGF beta, interleukin 1, and WNT-1. This protein interacts and thus activates TAK1 kinase. It has been shown that the C-terminal portion of this protein is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF beta, suggesting that this protein may function as a mediator between TGF beta receptors and TAK1.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203