TAB3 antibody

GeneTex

TAB3 antibody

9

IHC-P: 5 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

TAB3

TGF-beta activated kinase 1 (MAP3K7) binding protein 3

MAP3K7IP3, NAP1, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAB-3, TAK1-binding protein 3, TGF-beta activated kinase 1 and MAP3K7 binding protein 3, TGF-beta-activated kinase 1-binding protein 3, mitogen-activated protein kinase kinase kinase 7 interacting protein 3

Rabbit

IgG

TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203