Tagtociclib (hydrate)

MedChem Express

Tagtociclib (hydrate)

5

Research Use Only

99.95

C19H30N6O5

422.48

PF-07104091 hydrate is a potent and selective CDK2/cyclin E 1 and GSK3beta inhibitor, with K i s of 1.16 and 537.81 nM, respectively. PF-07104091 hydrate has anti-tumor activity for cyclin E 1 -amplified cancers. (patent WO2020157652A2).

O=C(C1=CC(COC)=NN1C)NC2=NNC([C@](CC3)([H])C[C@@H]3OC(NC(C)C)=O)=C2.[H]O[H]

2°C to 8°C

12352200